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What Causes of Prostate Cancer?


ByAgkidzone Staff
Updated: Nov 8, 2024

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Prostate cancer is a form of cancer that develops in the prostate, a gland located just below the bladder and an essential part of the male reproductive system. While most prostate cancers do not have a clear cause, researchers have identified several factors that can increase the likelihood of developing this disease. With 1.27 million cases diagnosed worldwide in 2018, prostate cancer remains the fourth most common cancer globally.

Excess Weight
Research shows that being overweight is a common trait among people diagnosed with prostate cancer. Doctors measure weight through body mass index (BMI), where a BMI between 25 and 30 indicates being overweight, and over 30 is classified as obese. While being overweight slightly raises the risk, obesity substantially increases it, highlighting the importance of maintaining a healthy weight.
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Aging
The risk of prostate cancer rises significantly with age, particularly after age 50. The exact link between aging and prostate cancer still requires further research, but a correlation seems likely. Interestingly, men of African-American descent face a higher risk starting around age 45 and often experience a more severe prognosis.
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Ethnic Background
Ethnicity also appears to influence prostate cancer risk. Studies show that men of African or Caribbean origin have a higher risk than those of Asian descent. This may suggest a genetic component, as many people of Caribbean descent also have African ancestry, pointing to ethnicity as a factor in prostate cancer risk.
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Family History
Having a family history of prostate cancer increases the likelihood of developing the disease. If a father or brother was diagnosed before age 60, the risk is even higher. Additionally, a family history of breast cancer can increase prostate cancer risk, especially in individuals with the BRCA1, BRCA2, or HPC1 genes, which are associated with hereditary cancers.
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Lack of Exercise
Exercise not only helps prevent obesity, a risk factor for prostate cancer, but it also promotes overall health. Physical activity releases hormones that may protect the prostate, and it strengthens vital areas of the body. Studies suggest that regular exercise can reduce the risk of many diseases, including prostate cancer.
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Dietary Factors
Diet plays a role in prostate cancer risk. Diets high in calcium may increase risk, while foods like tomatoes and red fruits might reduce it. Some research indicates that Brazil nuts, rich in selenium, could offer protective benefits against prostate cancer. Selenium, also found in foods like tuna, tofu, and mushrooms, is a trace mineral with possible anti-cancer properties.
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Height
Although height is often seen as a positive attribute, some studies suggest that taller men may experience faster cancer progression and a higher chance of the disease spreading. However, more research is needed to confirm this connection.
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History of Other Cancers
Individuals who have had cancers like kidney, bladder, or lung cancer may be at a slightly higher risk of developing prostate cancer later. This increased risk could be due to the impact of the initial illness on the body's overall immunity, but other factors may also play a role.
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Hormonal Influences
Hormone levels may impact prostate cancer risk, with particular attention given to high levels of IGF-1, a growth factor hormone. While IGF-1 naturally regulates cell life and death, elevated levels might sometimes stimulate cancer cell growth, making it a point of interest in prostate cancer research.
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Prostate Inflammation
The potential link between prostate inflammation and cancer is frequently studied. Some research supports a connection, while other studies show no correlation, indicating that further investigation is needed to clarify this relationship.
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